Acute myelocytic leukemia after exposure to asbestos
نویسندگان
چکیده
منابع مشابه
Intracerebral hemorrhagic dissemination of acute myelocytic leukemia.
A 10-year-old boy was admitted with left leg pain and fever of 38.9°C. The initial clinical impression was cellulitis. Laboratory findings included hemoglobin of 5 gjdl and white blood cell count of 206,OOOjmma The spleen was enlarged and multiple cervical lymph nodes were palpable. Bone marrow pathology was interpreted as acute myelocytic leukemia. The child was treated with antibiotics , but ...
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Acute myelocytic leukemia (AML) in both children and adults is a more complex and resistant disease than acute lymphocytic leukemia. Progress has been slower and therapy more complicated, but with intensive myelosuppressive induction and further postremission therapy one-third of such patients may now achieve longterm survival and probably be cured.’-5 In the Nordic countries (Denmark, Finland,...
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mic enzyme that converts daunorubicm to a principal metabolite, daunorubicino!, in the presence of NADPH. This enzyme, found in mammalian tissues and studied in rat tissue preparations and normal human blood components, is also present in human leukemic myeloblasts. The enzymes from both normal and leukemic leukocytes require NADPH for activity, have similar kinetics and substrate saturation ch...
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Marrow specimens obtained from 23 patients with acute myelocytic leukemia were exposed to cytosine arabinoside and/or daunorubicin in vitro, and the effects of these agents on colony formation in vitro was determined. Thymidine suicide indices were determined as well, which permitted a distinction to be made between kinetic and metabolic resistance to cytosine arabinoside. The sensitivity of th...
متن کاملMalignant Mesothelioma after Household Exposure to Asbestos
Malignant mesothelioma (MM) is an aggressive cancer that has been closely linked to asbestos exposure. Initially recognized as an occupational cancer in male workers, MM was later found to occur in their family members as well. We report the case of an 89-year-old female who presented with abdominal distention, pain, and findings consistent with malignant ascites. Family history was significant...
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ژورنال
عنوان ژورنال: Cancer
سال: 1988
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19880815)62:4<787::aid-cncr2820620424>3.0.co;2-8